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Attenuated Salmonella potentiate PD-L1 blockade immunotherapy in a preclinical model of colorectal cancer

The use of immune checkpoint inhibitors to treat cancer resulted in unprecedented and durable clinical benefits. However, the response rate among patients remains rather modest. Previous work from our laboratory demonstrated the efficacy of using attenuated bacteria as immunomodulatory anti-cancer a...

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Detalles Bibliográficos
Autores principales: Al-Saafeen, Besan H., Al-Sbiei, Ashraf, Bashir, Ghada, Mohamed, Yassir A., Masad, Razan J., Fernandez-Cabezudo, Maria J., al-Ramadi, Basel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807881/
https://www.ncbi.nlm.nih.gov/pubmed/36605208
http://dx.doi.org/10.3389/fimmu.2022.1017780