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Immune suppression of vaccine-induced CD8(+) T-cell responses by gamma retrovirus envelope is mediated by interleukin-10-producing CD4(+) T cells

Retroviral envelope (Env) proteins have long been recognized to exhibit immunosuppressive properties, which affect the CD8(+) T-cell response to an infection but also to immunization. Interestingly, we previously showed in the Friend murine leukemia virus (F-MuLV) model that the surface Env protein...

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Detalles Bibliográficos
Autores principales: Podschwadt, Philip, Malyshkina, Anna, Windmann, Sonja, Papadamakis, Athanasios, Kerkmann, Leonie, Lapuente, Dennis, Tenbusch, Matthias, Lu, Mengji, Schindler, Michael, Lang, Karl Sebastian, Hansen, Wiebke, Bayer, Wibke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807908/
https://www.ncbi.nlm.nih.gov/pubmed/36605206
http://dx.doi.org/10.3389/fimmu.2022.934399