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Immune suppression of vaccine-induced CD8(+) T-cell responses by gamma retrovirus envelope is mediated by interleukin-10-producing CD4(+) T cells
Retroviral envelope (Env) proteins have long been recognized to exhibit immunosuppressive properties, which affect the CD8(+) T-cell response to an infection but also to immunization. Interestingly, we previously showed in the Friend murine leukemia virus (F-MuLV) model that the surface Env protein...
Autores principales: | Podschwadt, Philip, Malyshkina, Anna, Windmann, Sonja, Papadamakis, Athanasios, Kerkmann, Leonie, Lapuente, Dennis, Tenbusch, Matthias, Lu, Mengji, Schindler, Michael, Lang, Karl Sebastian, Hansen, Wiebke, Bayer, Wibke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807908/ https://www.ncbi.nlm.nih.gov/pubmed/36605206 http://dx.doi.org/10.3389/fimmu.2022.934399 |
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