MiR-182-5p Mediated by Exosomes Derived From Bone Marrow Mesenchymal Stem Cell Attenuates Inflammatory Responses by Targeting TLR4 in a Mouse Model of Myocardial Infraction

Exosomes derived from mesenchymal stem cells (MSCs) could protect against myocardial infarction (MI). TLR4 is reported to play an important role in MI, while microRNA-182-5p (miR-182-5p) negatively regulates TLR4 expression. Therefore, we hypothesize that MSCs-derived exosomes overexpressing miR-182...

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Detalles Bibliográficos
Autores principales: Sun, Chuang, Li, Wei, Li, Yanhong, Chen, Jian, An, Huixian, Zeng, Guangwei, Wang, Tingting, Guo, Yazhou, Wang, Changying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807961/
https://www.ncbi.nlm.nih.gov/pubmed/36627935
http://dx.doi.org/10.4110/in.2022.22.e49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807961/
https://www.ncbi.nlm.nih.gov/pubmed/36627935
http://dx.doi.org/10.4110/in.2022.22.e49

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