DNA repair protein RAD52 is required for protecting G-quadruplexes in mammalian cells

G-quadruplex (G4)-forming DNA sequences are abundant in the human genome, and they are hot spots for inducing DNA double-strand breaks (DSBs) and genome instability. The mechanisms involved in protecting G4s and maintaining genome stability have not been fully elucidated. Here, we demonstrated that...

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Detalles Bibliográficos
Autores principales: Liu, Shuo, Wang, Zi, Shah, Sameer Bikram, Chang, Chia-Yu, Ai, Michael, Nguyen, Tran, Xiang, Rong, Wu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807996/
https://www.ncbi.nlm.nih.gov/pubmed/36470428
http://dx.doi.org/10.1016/j.jbc.2022.102770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807996/
https://www.ncbi.nlm.nih.gov/pubmed/36470428
http://dx.doi.org/10.1016/j.jbc.2022.102770

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