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Translational analysis and final efficacy of the AVETUX trial – Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer

INTRODUCTION: In metastatic colorectal cancer (mCRC), the efficacy of immune checkpoint blockade (ICB) has so far been limited to patients with microsatellite instability high tumors (MSI-H). Unfortunately, most mCRC patients suffer from non-immunogenic microsatellite stable (MSS) tumors. Therefore,...

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Detalles Bibliográficos
Autores principales: Tintelnot, Joseph, Ristow, Inka, Sauer, Markus, Simnica, Donjete, Schultheiß, Christoph, Scholz, Rebekka, Goekkurt, Eray, von Wenserski, Lisa, Willscher, Edith, Paschold, Lisa, Lorenzen, Sylvie, Riera-Knorrenschild, Jorge, Depenbusch, Reinhard, Ettrich, Thomas J., Dörfel, Steffen, Al-Batran, Salah-Eddin, Karthaus, Meinolf, Pelzer, Uwe, Hinke, Axel, Bauer, Marcus, Massa, Chiara, Seliger, Barbara, Wickenhauser, Claudia, Bokemeyer, Carsten, Hegewisch-Becker, Susanna, Binder, Mascha, Stein, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808039/
https://www.ncbi.nlm.nih.gov/pubmed/36605436
http://dx.doi.org/10.3389/fonc.2022.993611