Targeting the DLL/Notch Signaling Pathway in Cancer: Challenges and Advances in Clinical Development

The DLL/Notch signaling pathway plays an important role in cancer as a key driver in maintaining cancer stemness and inducing tumor angiogenesis. Many different types of DLL/Notch inhibitors have been developed and explored in clinical trials for cancer treatment, including small-molecule compounds...

Descripción completa

Detalles Bibliográficos
Autores principales: You, Weon-Kyoo, Schuetz, Thomas J., Lee, Sang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808372/
https://www.ncbi.nlm.nih.gov/pubmed/36223541
http://dx.doi.org/10.1158/1535-7163.MCT-22-0243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808372/
https://www.ncbi.nlm.nih.gov/pubmed/36223541
http://dx.doi.org/10.1158/1535-7163.MCT-22-0243

Ejemplares similares