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Targeting the DLL/Notch Signaling Pathway in Cancer: Challenges and Advances in Clinical Development
The DLL/Notch signaling pathway plays an important role in cancer as a key driver in maintaining cancer stemness and inducing tumor angiogenesis. Many different types of DLL/Notch inhibitors have been developed and explored in clinical trials for cancer treatment, including small-molecule compounds...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Association for Cancer Research
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808372/ https://www.ncbi.nlm.nih.gov/pubmed/36223541 http://dx.doi.org/10.1158/1535-7163.MCT-22-0243 |