Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer

The ability of a patient tumor to engraft an immunodeficient mouse is the strongest known independent indicator of poor prognosis in early-stage non–small cell lung cancer (NSCLC). Analysis of primary NSCLC proteomes revealed low-level expression of mitochondrial aconitase (ACO2) in the more aggress...

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Detalles Bibliográficos
Autores principales: Mirhadi, Shideh, Zhang, Wen, Pham, Nhu-An, Karimzadeh, Fereshteh, Pintilie, Melania, Tong, Jiefei, Taylor, Paul, Krieger, Jonathan, Pitcher, Bethany, Sykes, Jenna, Wybenga-Groot, Leanne, Fladd, Christopher, Xu, Jing, Wang, Tao, Cabanero, Michael, Li, Ming, Weiss, Jessica, Sakashita, Shingo, Zaslaver, Olga, Yu, Man, Caudy, Amy A., St-Pierre, Julie, Hawkins, Cynthia, Kislinger, Thomas, Liu, Geoffrey, Shepherd, Frances A., Tsao, Ming-Sound, Moran, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808373/
https://www.ncbi.nlm.nih.gov/pubmed/36214668
http://dx.doi.org/10.1158/1541-7786.MCR-22-0163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808373/
https://www.ncbi.nlm.nih.gov/pubmed/36214668
http://dx.doi.org/10.1158/1541-7786.MCR-22-0163

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