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Immune dysfunctions affecting bone marrow Vγ9Vδ2 T cells in multiple myeloma: Role of immune checkpoints and disease status

INTRODUCTION: Bone marrow (BM) Vγ9Vδ2 T cells are intrinsically predisposed to sense the immune fitness of the tumor microenvironment (TME) in multiple myeloma (MM) and monoclonal gammopathy of undetermined significance (MGUS). METHODS: In this work, we have used BM Vγ9Vδ2 T cells to interrogate the...

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Detalles Bibliográficos
Autores principales: Giannotta, Claudia, Castella, Barbara, Tripoli, Ezio, Grimaldi, Daniele, Avonto, Ilaria, D’Agostino, Mattia, Larocca, Alessandra, Kopecka, Joanna, Grasso, Mariella, Riganti, Chiara, Massaia, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808386/
https://www.ncbi.nlm.nih.gov/pubmed/36605214
http://dx.doi.org/10.3389/fimmu.2022.1073227