DNA damage stress-induced translocation of mutant FUS proteins into cytosolic granules and screening for translocation inhibitors

Fused in sarcoma/translated in liposarcoma (FUS) is an RNA-binding protein, and its mutations are associated with neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), through the DNA damage stress response, aberrant stress granule (SG) formation, etc. We previously reported tha...

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Detalles Bibliográficos
Autores principales: Nogami, Masahiro, Sano, Osamu, Adachi-Tominari, Keiko, Hayakawa-Yano, Yoshika, Furukawa, Takako, Iwata, Hidehisa, Ogi, Kazuhiro, Okano, Hideyuki, Yano, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808394/
https://www.ncbi.nlm.nih.gov/pubmed/36606141
http://dx.doi.org/10.3389/fnmol.2022.953365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808394/
https://www.ncbi.nlm.nih.gov/pubmed/36606141
http://dx.doi.org/10.3389/fnmol.2022.953365

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