HLA variants have different preferences to present proteins with specific molecular functions which are complemented in frequent haplotypes

Human leukocyte antigen (HLA) genes are the most polymorphic loci in the human genome and code for proteins that play a key role in guiding adaptive immune responses by presenting foreign and self peptides (ligands) to T cells. Each person carries up to 6 HLA class I variants (maternal and paternal...

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Detalles Bibliográficos
Autores principales: Karnaukhov, Vadim, Paes, Wayne, Woodhouse, Isaac B., Partridge, Thomas, Nicastri, Annalisa, Brackenridge, Simon, Shcherbinin, Dmitrii, Chudakov, Dmitry M., Zvyagin, Ivan V., Ternette, Nicola, Koohy, Hashem, Borrow, Persephone, Shugay, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808399/
https://www.ncbi.nlm.nih.gov/pubmed/36605212
http://dx.doi.org/10.3389/fimmu.2022.1067463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808399/
https://www.ncbi.nlm.nih.gov/pubmed/36605212
http://dx.doi.org/10.3389/fimmu.2022.1067463

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