Characterisation of the immune microenvironment of primary breast cancer and brain metastasis reveals depleted T-cell response associated to ARG2 expression

BACKGROUND: Immune checkpoint inhibition is an established treatment in programmed death-ligand 1 (PD-L1)-positive metastatic triple-negative (TN) breast cancer (BC). However, the immune landscape of breast cancer brain metastasis (BCBM) remains poorly defined. MATERIALS AND METHODS: The tumour-infi...

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Detalles Bibliográficos
Autores principales: Giannoudis, A., Varešlija, D., Sharma, V., Zakaria, R., Platt-Higgins, A., Rudland, P.S., Jenkinson, M.D., Young, L.S., Palmieri, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808462/
https://www.ncbi.nlm.nih.gov/pubmed/36423363
http://dx.doi.org/10.1016/j.esmoop.2022.100636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808462/
https://www.ncbi.nlm.nih.gov/pubmed/36423363
http://dx.doi.org/10.1016/j.esmoop.2022.100636

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