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Antitumor activity of lurbinectedin in combination with oral capecitabine in patients with metastatic breast cancer

BACKGROUND: Preclinical studies showed a synergistic effect for 5-fluorouracil and lurbinectedin against solid tumors. This phase I trial evaluated a combination of capecitabine plus lurbinectedin in patients with selected advanced solid tumors. Results in patients with relapsed metastatic breast ca...

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Detalles Bibliográficos
Autores principales: Awada, A.H., Boni, V., Moreno, V., Aftimos, P., Kahatt, C., Luepke-Estefan, X.E., Siguero, M., Fernandez-Teruel, C., Cullell-Young, M., Tabernero, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808480/
https://www.ncbi.nlm.nih.gov/pubmed/36455505
http://dx.doi.org/10.1016/j.esmoop.2022.100651