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Hypomethylation of thymosin β4 promoter is associated with glucocorticoid therapy in patients with acute-on-chronic hepatitis B-induced liver failure

BACKGROUND: We aimed to determine whether the methylation status of thymosin β4 (Tβ4) promoter reflects the severity of acute-on-chronic hepatitis B liver failure (ACHBLF) and whether glucocorticoids affect this status. METHODS: Fifty-six patients with ACHBLF, 45 with chronic hepatitis B (CHB) and 3...

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Detalles Bibliográficos
Autores principales: Wang, He, Qian, Yu, Wang, Jing-Wen, Fang, Yu, Fan, Yu-Chen, Liu, Hui-Hui, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808517/
https://www.ncbi.nlm.nih.gov/pubmed/35150577
http://dx.doi.org/10.1093/inthealth/ihac003