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Direct detection of natural selection in Bronze Age Britain

We developed a novel method for efficiently estimating time-varying selection coefficients from genome-wide ancient DNA data. In simulations, our method accurately recovers selective trajectories and is robust to misspecification of population size. We applied it to a large data set of ancient and p...

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Detalles Bibliográficos
Autores principales: Mathieson, Iain, Terhorst, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808619/
https://www.ncbi.nlm.nih.gov/pubmed/36316157
http://dx.doi.org/10.1101/gr.276862.122