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Methyl-SNP-seq reveals dual readouts of methylome and variome at molecule resolution while enabling target enrichment
Covalent modifications of genomic DNA are crucial for most organisms to survive. Amplicon-based high-throughput sequencing technologies erase all DNA modifications to retain only sequence information for the four canonical nucleobases, necessitating specialized technologies for ascertaining epigenet...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808626/ https://www.ncbi.nlm.nih.gov/pubmed/36332968 http://dx.doi.org/10.1101/gr.277080.122 |