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Inhibition of Phosphoinositide 3-Kinase Gamma Protects Endothelial Cells via the Akt Signaling Pathway in Sepsis-Induced Acute Kidney Injury

INTRODUCTION: Sepsis is a primary cause of death in critically ill patients and is characterized by multiple organ dysfunction, including sepsis-induced acute kidney injury (AKI), which contributes to high mortality in sepsis. However, its pathophysiological mechanisms remain unclear. The kidney has...

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Detalles Bibliográficos
Autores principales: Li, Han, Xu, Jun-Xian, Cheng, Tiao-Chun, Tian, Li-Jun, Lin, Jin-Feng, Luo, Xi, Bian, Zhao-Lian, Han, Xu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808661/
https://www.ncbi.nlm.nih.gov/pubmed/36130530
http://dx.doi.org/10.1159/000526916