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The rapid and highly parallel identification of antibodies with defined biological activities by SLISY

The therapeutic applications of antibodies are manifold and the emergence of SARS-CoV-2 provides a cogent example of the value of rapidly identifying biologically active antibodies. We describe an approach called SLISY (Sequencing-Linked ImmunoSorbent assaY) that in a single experiment can assess th...

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Detalles Bibliográficos
Autores principales: Lu, Steve, Mattox, Austin K., Aitana Azurmendi, P., Christodoulou, Ilias, Wright, Katharine M., Popoli, Maria, Chen, Zan, Sur, Surojit, Li, Yana, Bonifant, Challice L., Bettegowda, Chetan, Papadopoulos, Nickolas, Zhou, Shibin, Gabelli, Sandra B., Vogelstein, Bert, Kinzler, Kenneth W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808734/
https://www.ncbi.nlm.nih.gov/pubmed/36596784
http://dx.doi.org/10.1038/s41467-022-35668-6