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Anti-PD-1 immune-related adverse events are associated with high therapeutic antibody fixation on T cells

Immune checkpoint inhibitors (ICI) widely improved the treatment of solid and hematologic malignancies. Yet, a remarkable proportion of patients receiving ICI develop immune related adverse events (irAEs) which are difficult to define as treatment-related. This underlines the need to develop a bioma...

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Detalles Bibliográficos
Autores principales: Gazzano, Marianne, Parizot, Christophe, Psimaras, Dimitri, Vozy, Aurore, Baron, Marine, Abbar, Baptiste, Fallet, Vincent, Litvinova, Elena, Canellas, Anthony, Birzu, Cristina, Pourcher, Valérie, Touat, Mehdi, Weiss, Nicolas, Demeret, Sophie, Roos-Weil, Damien, Spano, Jean-Philippe, Lebbe, Celeste, Salem, Joe-Elie, Cadranel, Jacques, Hervier, Baptiste, Gorochov, Guy, Guihot, Amélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808779/
https://www.ncbi.nlm.nih.gov/pubmed/36605194
http://dx.doi.org/10.3389/fimmu.2022.1082084