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ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury

The lung exhibits a robust, multifaceted regenerative response to severe injuries such as influenza infection, during which quiescent lung-resident epithelial progenitors participate in two distinct reparative pathways: functionally beneficial regeneration via alveolar type 2 (AT2) cell proliferatio...

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Detalles Bibliográficos
Autores principales: Weiner, Aaron I., Zhao, Gan, Zayas, Hanna M., Holcomb, Nicolas P., Adams-Tzivelekidis, Stephanie, Wong, Joanna, Gentile, Maria E., Reddy, Dyuthi, Wei, Joey, Palashikar, Gargi, Quansah, Kwaku K., Vaughan, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808897/
https://www.ncbi.nlm.nih.gov/pubmed/36516758
http://dx.doi.org/10.1016/j.celrep.2022.111805