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ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury
The lung exhibits a robust, multifaceted regenerative response to severe injuries such as influenza infection, during which quiescent lung-resident epithelial progenitors participate in two distinct reparative pathways: functionally beneficial regeneration via alveolar type 2 (AT2) cell proliferatio...
Autores principales: | Weiner, Aaron I., Zhao, Gan, Zayas, Hanna M., Holcomb, Nicolas P., Adams-Tzivelekidis, Stephanie, Wong, Joanna, Gentile, Maria E., Reddy, Dyuthi, Wei, Joey, Palashikar, Gargi, Quansah, Kwaku K., Vaughan, Andrew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808897/ https://www.ncbi.nlm.nih.gov/pubmed/36516758 http://dx.doi.org/10.1016/j.celrep.2022.111805 |
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