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Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria

BACKGROUND: The contribution of artefenomel to the clinical and parasiticidal activity of ferroquine and artefenomel in combination in uncomplicated Plasmodium falciparum malaria was investigated. METHODS: This Phase 2a, randomized, open-label, parallel-group study was conducted from 11th September...

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Detalles Bibliográficos
Autores principales: Gansane, Adama, Lingani, Moussa, Yeka, Adoke, Nahum, Alain, Bouyou-Akotet, Marielle, Mombo-Ngoma, Ghyslain, Kaguthi, Grace, Barceló, Catalina, Laurijssens, Bart, Cantalloube, Cathy, Macintyre, Fiona, Djeriou, Elhadj, Jessel, Andreas, Bejuit, Raphaël, Demarest, Helen, Marrast, Anne Claire, Debe, Siaka, Tinto, Halidou, Kibuuka, Afizi, Nahum, Diolinda, Mawili-Mboumba, Denise Patricia, Zoleko-Manego, Rella, Mugenya, Irene, Olewe, Frederick, Duparc, Stephan, Ogutu, Bernhards
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809015/
https://www.ncbi.nlm.nih.gov/pubmed/36597076
http://dx.doi.org/10.1186/s12936-022-04420-2