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Total coumarins of Pileostegia tomentella induces cell death in SCLC by reprogramming metabolic patterns, possibly through attenuating β-catenin/AMPK/SIRT1

BACKGROUND: Small-cell lung cancer (SCLC) is a high malignant and high energy-consuming type of lung cancer. Total coumarins of Pileostegia tomentella (TCPT) from a traditional folk medicine of Yao minority, is a potential anti-cancer mixture against SCLC, but the pharmacological and molecular mecha...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Wu, Kun, Li, Li, Zhu, Fucui, Wang, Li, Su, Hua, Li, Ying, Lu, Lu, Lu, Guoshou, Hu, Xiaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809065/
https://www.ncbi.nlm.nih.gov/pubmed/36597133
http://dx.doi.org/10.1186/s13020-022-00703-7