Association of immune-related adverse events with the outcomes of immune checkpoint inhibitors in patients with dMMR/MSI-H metastatic colorectal cancer

BACKGROUND: Immune checkpoint inhibitors (ICIs) show a tremendous activity in microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC), but a consistent fraction of patients does not respond. Prognostic/predictive markers are needed. Despite previous investigations in other tumor...

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Detalles Bibliográficos
Autores principales: Nasca, Vincenzo, Barretta, Francesco, Corti, Francesca, Lonardi, Sara, Niger, Monica, Elez, Maria Elena, Fakih, Marwan, Jayachandran, Priya, Shah, Aakash Tushar, Salati, Massimiliano, Fenocchio, Elisabetta, Salvatore, Lisa, Cremolini, Chiara, Ros, Javier, Ambrosini, Margherita, Mazzoli, Giacomo, Intini, Rossana, Overman, Michael J, Miceli, Rosalba, Pietrantonio, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809233/
https://www.ncbi.nlm.nih.gov/pubmed/36593068
http://dx.doi.org/10.1136/jitc-2022-005493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809233/
https://www.ncbi.nlm.nih.gov/pubmed/36593068
http://dx.doi.org/10.1136/jitc-2022-005493

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