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Association of immune-related adverse events with the outcomes of immune checkpoint inhibitors in patients with dMMR/MSI-H metastatic colorectal cancer
BACKGROUND: Immune checkpoint inhibitors (ICIs) show a tremendous activity in microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC), but a consistent fraction of patients does not respond. Prognostic/predictive markers are needed. Despite previous investigations in other tumor...
Autores principales: | Nasca, Vincenzo, Barretta, Francesco, Corti, Francesca, Lonardi, Sara, Niger, Monica, Elez, Maria Elena, Fakih, Marwan, Jayachandran, Priya, Shah, Aakash Tushar, Salati, Massimiliano, Fenocchio, Elisabetta, Salvatore, Lisa, Cremolini, Chiara, Ros, Javier, Ambrosini, Margherita, Mazzoli, Giacomo, Intini, Rossana, Overman, Michael J, Miceli, Rosalba, Pietrantonio, Filippo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809233/ https://www.ncbi.nlm.nih.gov/pubmed/36593068 http://dx.doi.org/10.1136/jitc-2022-005493 |
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