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Anti-PAI-1 Monoclonal Antibody Inhibits the Metastasis and Growth of Esophageal Squamous Cell Carcinoma

Plasminogen activator inhibitor (PAI-1) is highly expressed in esophageal squamous cell carcinoma (ESCC) and strongly contributes to metastasis, making it a potential target for ESCC therapy. However, the antibodies and inhibitors targeting PAI-1 have not shown good therapeutic effect in the in vivo...

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Detalles Bibliográficos
Autores principales: Zheng, Yutian, Meng, Lin, Qu, Like, Zhao, Chuanke, Wang, Lixin, Liu, Caiyun, Shou, Chengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809335/
https://www.ncbi.nlm.nih.gov/pubmed/36605486
http://dx.doi.org/10.7150/jca.77888