The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma

Temozolomide (TMZ) is a conventional chemotherapeutic drug for glioma, however, its clinical application and efficacy is severely restricted by its drug resistance properties. O6-methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme, which can repair the DNA damage caused by TMZ. A large...

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Detalles Bibliográficos
Autores principales: Xu, Haoyue, Zhang, Yongkang, Li, Linfeng, Ren, Yanhong, Qian, Feng, Wang, Lansheng, Ma, Hongwei, Quan, Ankang, Liu, Hongmei, Yu, Rutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809344/
https://www.ncbi.nlm.nih.gov/pubmed/36579448
http://dx.doi.org/10.1080/10717544.2022.2152911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809344/
https://www.ncbi.nlm.nih.gov/pubmed/36579448
http://dx.doi.org/10.1080/10717544.2022.2152911

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