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Formulation and characterization of lamotrigine nasal insert targeted brain for enhanced epilepsy treatment

Lamotrigine. (LMT) is a triazine drug has an antiepileptic effect but with low water solubility, dissolution rate and thus therapeutic effect. Spanlastics are nano-vesicular carriers’ act as site-specific drug delivery system. Intranasal route could direct the drug from nose to brain and provide a f...

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Detalles Bibliográficos
Autores principales: Abdelmonem, Rehab, El-Enin, Hadel A. Abo, Abdelkader, Ghada, Abdel-Hakeem, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809415/
https://www.ncbi.nlm.nih.gov/pubmed/36579655
http://dx.doi.org/10.1080/10717544.2022.2163321