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Formulation and characterization of lamotrigine nasal insert targeted brain for enhanced epilepsy treatment
Lamotrigine. (LMT) is a triazine drug has an antiepileptic effect but with low water solubility, dissolution rate and thus therapeutic effect. Spanlastics are nano-vesicular carriers’ act as site-specific drug delivery system. Intranasal route could direct the drug from nose to brain and provide a f...
Autores principales: | Abdelmonem, Rehab, El-Enin, Hadel A. Abo, Abdelkader, Ghada, Abdel-Hakeem, Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809415/ https://www.ncbi.nlm.nih.gov/pubmed/36579655 http://dx.doi.org/10.1080/10717544.2022.2163321 |
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