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LncRNA GAS5 enhances tumor stem cell-like medicated sensitivity of paclitaxel and inhibits epithelial-to-mesenchymal transition by targeting the miR-18a-5p/STK4 pathway in prostate cancer

The onset of prostate cancer (PCa) is often hidden, and recurrence and metastasis are more likely to occur due to chemotherapy resistance. Herein, we identified downregulated long noncoding RNA (lncRNA) growth arrest-specific 5 (GAS5) in PCa that was associated with metastasis and paclitaxel resista...

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Detalles Bibliográficos
Autores principales: Lu, Ting-Ting, Tao, Xia, Li, Hua-Lei, Gai, Ling, Huang, Hua, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809493/
https://www.ncbi.nlm.nih.gov/pubmed/35295003
http://dx.doi.org/10.4103/aja2021117