Vacuole fragmentation depends on a novel Atg18-containing retromer-complex

The yeast PROPPIN Atg18 folds as a β-propeller with two binding sites for phosphatidylinositol-3-phosphate (PtdIns3P) and PtdIns(3,5)P(2) at its circumference. Membrane insertion of an amphipathic loop of Atg18 leads to membrane tubulation and fission. Atg18 has known functions at the PAS during mac...

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Detalles Bibliográficos
Autores principales: Marquardt, Lisa, Taylor, Matthew, Kramer, Florian, Schmitt, Kerstin, Braus, Gerhard H., Valerius, Oliver, Thumm, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809942/
https://www.ncbi.nlm.nih.gov/pubmed/35574911
http://dx.doi.org/10.1080/15548627.2022.2072656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809942/
https://www.ncbi.nlm.nih.gov/pubmed/35574911
http://dx.doi.org/10.1080/15548627.2022.2072656

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