Proteotoxic stress disrupts epithelial integrity by inducing MTOR sequestration and autophagy overactivation

Macroautophagy/autophagy, an evolutionarily conserved degradation system, serves to clear intracellular components through the lysosomal pathway. Mounting evidence has revealed cytoprotective roles of autophagy; however, the intracellular causes of overactivated autophagy, which has cytotoxic effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Xiaoxiang, Zhang, Pei, Zhao, Hongyu, Zheng, Hui, Zheng, Kai, Zhang, Hong, Zhang, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809964/
https://www.ncbi.nlm.nih.gov/pubmed/35521960
http://dx.doi.org/10.1080/15548627.2022.2071381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809964/
https://www.ncbi.nlm.nih.gov/pubmed/35521960
http://dx.doi.org/10.1080/15548627.2022.2071381

Ejemplares similares