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Proteotoxic stress disrupts epithelial integrity by inducing MTOR sequestration and autophagy overactivation
Macroautophagy/autophagy, an evolutionarily conserved degradation system, serves to clear intracellular components through the lysosomal pathway. Mounting evidence has revealed cytoprotective roles of autophagy; however, the intracellular causes of overactivated autophagy, which has cytotoxic effect...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809964/ https://www.ncbi.nlm.nih.gov/pubmed/35521960 http://dx.doi.org/10.1080/15548627.2022.2071381 |