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Hemagglutinin Stability Determines Influenza A Virus Susceptibility to a Broad-Spectrum Fusion Inhibitor Arbidol

[Image: see text] Understanding mechanisms of resistance to antiviral inhibitors can reveal nuanced features of targeted viral mechanisms and, in turn, lead to improved strategies for inhibitor design. Arbidol is a broad-spectrum antiviral that binds to and prevents the fusion-associated conformatio...

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Detalles Bibliográficos
Autores principales: Li, Zhenyu, Li, Tian, Liu, Meisui, Ivanovic, Tijana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810120/
https://www.ncbi.nlm.nih.gov/pubmed/35819162
http://dx.doi.org/10.1021/acsinfecdis.2c00178