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SARS-CoV-2 mRNA vaccination exposes progressive adaptive immune dysfunction in patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) patients have lower seroconversion rates and antibody titers following SARS-CoV-2 vaccination, but the reasons for this diminished response are poorly understood. Here, we studied humoral and cellular responses in 95 CLL patients and 30 healthy controls after two B...

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Detalles Bibliográficos
Autores principales: Qin, Kai, Honjo, Kazuhito, Sherrill-Mix, Scott, Liu, Weimin, Stoltz, Regina, Oman, Allisa K., Hall, Lucinda A., Li, Ran, Sterrett, Sarah, Frederick, Ellen R., Lancaster, Jeffrey R., Narkhede, Mayur, Mehta, Amitkumar, Ogunsile, Foluso J., Patel, Rima B., Ketas, Thomas J., Cruz Portillo, Victor M, Cupo, Albert, Larimer, Benjamin M., Bansal, Anju, Goepfert, Paul A., Hahn, Beatrice H., Davis, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810225/
https://www.ncbi.nlm.nih.gov/pubmed/36597532
http://dx.doi.org/10.1101/2022.12.19.22283645