ESCRT recruitment to mRNA-encoded SARS-CoV-2 spike induces virus-like particles and enhanced antibody responses

Prime-boost regimens for COVID-19 vaccines elicit poor antibody responses against Omicron-based variants and employ frequent boosters to maintain antibody levels. We present a natural infection-mimicking technology that combines features of mRNA- and protein nanoparticle-based vaccines through encod...

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Detalles Bibliográficos
Autores principales: Hoffmann, Magnus A. G., Yang, Zhi, Huey-Tubman, Kathryn E., Cohen, Alexander A., Gnanapragasam, Priyanthi N. P., Nakatomi, Leesa M., Storm, Kaya N., Moon, Woohyun J., Lin, Paulo J.C., Bjorkman, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810232/
https://www.ncbi.nlm.nih.gov/pubmed/36597535
http://dx.doi.org/10.1101/2022.12.26.521940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810232/
https://www.ncbi.nlm.nih.gov/pubmed/36597535
http://dx.doi.org/10.1101/2022.12.26.521940

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