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KRAS Mutation in Pediatric Intracranial Germ Cell Tumors

BACKGROUND: Intracranial germ cell tumors (IGCTs) are rare, highly curable neoplasms. KRAS is a gene in the KIT/RAS signaling pathway, and KRAS mutations have been reported in patients diagnosed with IGCTs. OBJECTIVES: To describe the clinicopathologic and molecular features of KRAS mutation and the...

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Detalles Bibliográficos
Autores principales: Khaiman, Chusana, Techavichit, Piti, Poparn, Hansamon, Chiengthong, Kanhatai, Lauhasurayotin, Supanun, Sosothikul, Darintr, Shotelersuk, Kanjana, Nantavithya, Chonnipa, Jakchairoongruang, Ketsuda, Amornfa, Jiraphorn, Khongkhaduead, Ekkachai, Santisukwongchote, Sakun, Teerapakpinyo, Chinachote, Shuangshoti, Shanop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810291/
https://www.ncbi.nlm.nih.gov/pubmed/36172682
http://dx.doi.org/10.31557/APJCP.2022.23.9.3179