MHY2251, a New SIRT1 Inhibitor, Induces Apoptosis via JNK/p53 Pathway in HCT116 Human Colorectal Cancer Cells

Sirtuins (SIRTs) belong to the nicotinamide adenine dinucleotide (NAD+)-dependent class III histone deacetylase family. They are key regulators of cellular and physiological processes, such as cell survival, senescence, differentiation, DNA damage and stress response, cellular metabolism, and aging....

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Detalles Bibliográficos
Autores principales: Kang, Yong Jung, Kwon, Young Hoon, Jang, Jung Yoon, Lee, Jun Ho, Lee, Sanggwon, Park, Yujin, Moon, Hyung Ryong, Chung, Hae Young, Kim, Nam Deuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810441/
https://www.ncbi.nlm.nih.gov/pubmed/35811306
http://dx.doi.org/10.4062/biomolther.2022.044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810441/
https://www.ncbi.nlm.nih.gov/pubmed/35811306
http://dx.doi.org/10.4062/biomolther.2022.044

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