Identification of Small GTPases That Phosphorylate IRF3 through TBK1 Activation Using an Active Mutant Library Screen

Interferon regulatory factor 3 (IRF3) integrates both immunological and non-immunological inputs to control cell survival and death. Small GTPases are versatile functional switches that lie on the very upstream in signal transduction pathways, of which duration of activation is very transient. The l...

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Detalles Bibliográficos
Autores principales: Yu, Jae-Hyun, Moon, Eun-Yi, Kim, Jiyoon, Koo, Ja Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810446/
https://www.ncbi.nlm.nih.gov/pubmed/36579460
http://dx.doi.org/10.4062/biomolther.2022.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810446/
https://www.ncbi.nlm.nih.gov/pubmed/36579460
http://dx.doi.org/10.4062/biomolther.2022.119

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