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Growth Factors Upregulated by Uric Acid Affect Guanine Deaminase-Induced Melanogenesis

Uric acid produced by guanine deaminase (GDA) is involved in photoaging and hyperpigmentation. Reactive oxygen species (ROS) generated by uric acid plays a role in photoaging. However, the mechanism by which uric acid stimulates melanogenesis in GDA-overexpressing keratinocytes is unclear. Keratinoc...

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Detalles Bibliográficos
Autores principales: Kim, Nan-Hyung, Lee, Ai-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810452/
https://www.ncbi.nlm.nih.gov/pubmed/36549672
http://dx.doi.org/10.4062/biomolther.2022.137