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A fast, efficient, and scalable method for purifying recombinant SARS-CoV-2 spike protein
Recombinant SARS-CoV-2 trimeric spike protein produced by mammalian cell culture is a potential candidate for a COVID-19 vaccine. However, this protein is much larger than most typical biopharmaceutical proteins and its large-scale manufacture is therefore challenging. Particularly, its purification...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Published by Elsevier B.V.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810479/ https://www.ncbi.nlm.nih.gov/pubmed/36603473 http://dx.doi.org/10.1016/j.jchromb.2022.123579 |