Distinct changes in endosomal composition promote NLRP3 inflammasome activation

Inflammasome complexes are pivotal in the innate immune response. The NLR family pyrin domain containing protein 3 (NLRP3) inflammasome is activated in response to a broad variety of cellular stressors. However, a primary and converging sensing mechanism by the NLRP3 receptor initiating inflammasome...

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Detalles Bibliográficos
Autores principales: Zhang, Zhirong, Venditti, Rossella, Ran, Li, Liu, Zengzhen, Vivot, Karl, Schürmann, Annette, Bonifacino, Juan S., De Matteis, Maria Antonietta, Ricci, Romeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810532/
https://www.ncbi.nlm.nih.gov/pubmed/36443515
http://dx.doi.org/10.1038/s41590-022-01355-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810532/
https://www.ncbi.nlm.nih.gov/pubmed/36443515
http://dx.doi.org/10.1038/s41590-022-01355-3

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