Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells

The kinase LCK and CD4/CD8 co-receptors are crucial components of the T cell antigen receptor (TCR) signaling machinery, leading to key T cell fate decisions. Despite decades of research, the roles of CD4–LCK and CD8–LCK interactions in TCR triggering in vivo remain unknown. In this study, we create...

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Detalles Bibliográficos
Autores principales: Horkova, Veronika, Drobek, Ales, Paprckova, Darina, Niederlova, Veronika, Prasai, Avishek, Uleri, Valeria, Glatzova, Daniela, Kraller, Markus, Cesnekova, Michaela, Janusova, Sarka, Salyova, Eva, Tsyklauri, Oksana, Kadlecek, Theresa A., Krizova, Katerina, Platzer, René, Schober, Kilian, Busch, Dirk H., Weiss, Arthur, Huppa, Johannes B., Stepanek, Ondrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810533/
https://www.ncbi.nlm.nih.gov/pubmed/36564464
http://dx.doi.org/10.1038/s41590-022-01366-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810533/
https://www.ncbi.nlm.nih.gov/pubmed/36564464
http://dx.doi.org/10.1038/s41590-022-01366-0

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