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Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells

Maternal immune activation (MIA) during prenatal development is an environmental risk factor for psychiatric disorders including schizophrenia (SZ). Converging lines of evidence from human and animal model studies suggest that elevated cytokine levels in the maternal and fetal compartments are an im...

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Detalles Bibliográficos
Autores principales: Bhat, Anjali, Irizar, Haritz, Couch, Amalie C.M., Raval, Pooja, Duarte, Rodrigo R.R., Dutan Polit, Lucia, Hanger, Bjorn, Powell, Timothy, Deans, P.J. Michael, Shum, Carole, Nagy, Roland, McAlonan, Grainne, Iyegbe, Conrad O., Price, Jack, Bramon, Elvira, Bhattacharyya, Sagnik, Vernon, Anthony C., Srivastava, Deepak P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810540/
https://www.ncbi.nlm.nih.gov/pubmed/35716830
http://dx.doi.org/10.1016/j.bbi.2022.06.010