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Induced pluripotent stem cell-derived and directly reprogrammed neurons to study neurodegenerative diseases: The impact of aging signatures

Many diseases of the central nervous system are age-associated and do not directly result from genetic mutations. These include late-onset neurodegenerative diseases (NDDs), which represent a challenge for biomedical research and drug development due to the impossibility to access to viable human br...

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Detalles Bibliográficos
Autores principales: Aversano, Simona, Caiazza, Carmen, Caiazzo, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810544/
https://www.ncbi.nlm.nih.gov/pubmed/36620769
http://dx.doi.org/10.3389/fnagi.2022.1069482