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Decreased Astrocytic CCL2 Accounts for BAF-312 Effect on PBMCs Transendothelial Migration Through a Blood Brain Barrier in Vitro Model

Disruption of the blood brain barrier (BBB) is a common event in several neurological diseases and in particular, in multiple sclerosis (MS), it contributes to the infiltration of the central nervous system by peripheral inflammatory cells. Sphingosine-1-phosphate (S1P) is a bioactive molecule with...

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Detalles Bibliográficos
Autores principales: Spampinato, Simona F., Merlo, Sara, Costantino, Giuseppe, Sano, Yasuteru, Kanda, Takashi, Sortino, Maria Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810569/
https://www.ncbi.nlm.nih.gov/pubmed/34599741
http://dx.doi.org/10.1007/s11481-021-10016-5