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Decreased Astrocytic CCL2 Accounts for BAF-312 Effect on PBMCs Transendothelial Migration Through a Blood Brain Barrier in Vitro Model
Disruption of the blood brain barrier (BBB) is a common event in several neurological diseases and in particular, in multiple sclerosis (MS), it contributes to the infiltration of the central nervous system by peripheral inflammatory cells. Sphingosine-1-phosphate (S1P) is a bioactive molecule with...
Autores principales: | Spampinato, Simona F., Merlo, Sara, Costantino, Giuseppe, Sano, Yasuteru, Kanda, Takashi, Sortino, Maria Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810569/ https://www.ncbi.nlm.nih.gov/pubmed/34599741 http://dx.doi.org/10.1007/s11481-021-10016-5 |
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