A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers

Mutations of the RAS oncogene are found in around 30% of all human cancers yet direct targeting of RAS is still considered clinically impractical except for the KRAS(G12C) mutant. Here we report that RAS-ON (RASON), a novel protein encoded by the long intergenic non-protein coding RNA 00673 (LINC006...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Rongjie, Li, Fanying, Zhang, Maolei, Xia, Xin, Wu, Jianzhuang, Gao, Xinya, Zhou, Huangkai, Zhang, Zhi, Huang, Nunu, Yang, Xuesong, Zhang, Yaliang, Shen, Shunli, Kang, Tiebang, Liu, Zexian, Xiao, Feizhe, Yao, Hongwei, Xu, Jianbo, Yan, Chao, Zhang, Nu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810732/
https://www.ncbi.nlm.nih.gov/pubmed/36241718
http://dx.doi.org/10.1038/s41422-022-00726-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810732/
https://www.ncbi.nlm.nih.gov/pubmed/36241718
http://dx.doi.org/10.1038/s41422-022-00726-7

Ejemplares similares