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NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer

The emergence of resistance to systemic therapies in pancreatic ductal adenocarcinoma (PDAC) is still a major obstacle in clinical practice. Both, constitutive and inducible NF-κB activity are known as key players in this context. To identify differentially expressed and TRAIL resistance mediating N...

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Detalles Bibliográficos
Autores principales: Geismann, Claudia, Hauser, Charlotte, Grohmann, Frauke, Schneeweis, Christian, Bölter, Nico, Gundlach, Jan-Paul, Schneider, Günter, Röcken, Christoph, Meinhardt, Christian, Schäfer, Heiner, Schreiber, Stefan, Arlt, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810737/
https://www.ncbi.nlm.nih.gov/pubmed/36596765
http://dx.doi.org/10.1038/s41419-022-05535-9